Aviv Regev

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region

Mapping the brain, one neuron at a time Spatial transcriptomics can link molecularly described cell types to their anatomical positions and functional roles. Moffitt et al. used...

Full-length transcriptome assembly from RNA-Seq data without a reference genome

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

Large intergenic noncoding RNAs (lincRNAs) are emerging as key regulators of diverse cellular processes. Determining the function of individual lincRNAs remains a challenge. Rec...

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of...

Spatial reconstruction of single-cell gene expression data

Spatial localization is a key determinant of cellular fate and behavior, but methods for spatially resolved, transcriptome-wide gene expression profiling across complex tissues ...

Revealing the vectors of cellular identity with single-cell genomics

Single-cell genomics has now made it possible to create a comprehensive atlas of human cells. At the same time, it has reopened definitions of a cell's identity and of the ways ...