Edward E. Knaus - Researcher Profile

Publications

2 shown

Fluorophore‐Labeled Cyclooxygenase‐2 Inhibitors for the Imaging of Cyclooxygenase‐2 Overexpression in Cancer: Synthesis and Biological Studies

Atul Bhardwaj , Jatinder Kaur , Frank Wuest +1 more

Abstract A group of cyclooxygenase‐2 (COX‐2)‐specific fluorescent cancer biomarkers were synthesized by linking the anti‐inflammatory drugs ibuprofen, ( S )‐naproxen, and celeco...

2013 ChemMedChem 42 citations

Rofecoxib Analogues Possessing a Nitric Oxide Donor Sulfohydroxamic Acid (SO<sub>2</sub>NHOH) Cyclooxygenase‐2 Pharmacophore: Synthesis, Molecular Modeling, and Biological Evaluation as Anti‐inflammatory Agents

Atul Bhardwaj , Zhangjian Huang , Jatinder Kaur +1 more

Expertly tailored! The development of safe anti-inflammatory (AI) agents that are highly selective COX-2 inhibitors has been challenging, as indicated by the clinical withdrawal...

2011 ChemMedChem 27 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 69
Institution: University of Alberta

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Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.