Eric D. Green

Initial sequencing and comparative analysis of the mouse genome

Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

We define a “threaded blockset,” which is a novel generalization of the classic notion of a multiple alignment. A new computer program called TBA (for “threaded blockset aligner...

Assessing Mapping Progress in the Human Genome Project

The Human Genome Project

The recently initiated human genome project is a large international effort to elucidate the genetic architecture of the genomes of man and several model organisms. The initial ...

An integrated encyclopedia of DNA elements in the human genome

The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) pro...