A conventional Mendelian randomization analysis assesses the causal effect of a risk factor on an outcome by using genetic variants that are solely associated with the risk fact...
The genetic findings support a causal effect of triglycerides on CHD risk, but a causal role for HDL-C, though possible, remains less certain.
Polygenic scores have recently been used to summarise genetic effects among an ensemble of markers that do not individually achieve significance in a large-scale association stu...
Abstract Odds ratios or other effect sizes estimated from genome scans are upwardly biased, because only the top‐ranking associations are reported, and moreover only if they rea...
h-index: Number of publications with at least h citations each.