H. Robert Horvitz

MicroRNA expression profiles classify human cancers

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Heterochronic Mutants of the Nematode <i>Caenorhabditis elegans</i>

Mutations in the Caenorhabditis elegans genes lin-14 , lin-28 , and lin-29 cause heterochronic developmental defects: the timing of specific developmental events in several tiss...

Microarray analysis of microRNA expression in the developing mammalian brain

Abstract Background MicroRNAs are a large new class of tiny regulatory RNAs found in nematodes, plants, insects and mammals. MicroRNAs are thought to act as post-transcriptional...

The GABAergic nervous system of Caenorhabditis elegans

gamma-Aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in vertebrates and invertebrates. GABA receptors are the target of anxiolytic, antiepileptic and ...

MicroRNA Expression in Zebrafish Embryonic Development

MicroRNAs (miRNAs) are small noncoding RNAs, about 21 nucleotides in length, that can regulate gene expression by base-pairing to partially complementary mRNAs. Regulation by mi...