Discovery of a Novel Target Inhibitor Theaflavin against UDP-Glucose Pyrophosphorylase 2 and Its Role in Attenuating the Malignant Phenotype of Liver Cancer Cells via Perturbation of Glucose Metabolism
UDP-glucose pyrophosphorylase 2 (UGP2), the unique mammalian enzyme converting glucose-1-phosphate to UDP-glucose, is upregulated in hepatocellular carcinoma (HCC) and other mal...