Jean Paul Thiery

Complex networks orchestrate epithelial–mesenchymal transitions

Epithelial-Mesenchymal Transitions in Development and Disease

Prototypical Type I E-cadherin and Type II Cadherin-7 Mediate Very Distinct Adhesiveness through Their Extracellular Domains

Using a dual pipette assay that measures the force required to separate adherent cell doublets, we have quantitatively compared intercellular adhesiveness mediated by Type I (E-...

Modulation of several waves of gene expression during FGF‐1 induced epithelial‐mesenchymal transition of carcinoma cells

Abstract During epithelial‐mesenchymal transition (EMT), epithelial cells are converted into isolated motile and invasive mesenchymal cells. In model systems, EMT is induced mos...

Regulation of <i>XSnail2</i> expression by Rho GTPases

Abstract We analyzed the effects of Rho GTPases on XSnail2 expression during neural crest (NC) ontogeny in Xenopus laevis embryos. The ectopic expression of both dominant‐negati...

Targeted therapies in control of EMT in carcinoma and fibrosis

Early events in cell adhesion and polarity during epithelial-mesenchymal transition

During evolution from primitive species, a mechanism, termed epithelial-mesenchymal transition (EMT), was established to create mesenchymal cells from a pre-existing epithelial ...