John A. Hickman - Researcher Profile

Publications

2 shown

Commitment to cell death measured by loss of clonogenicity is separable from the appearance of apoptotic markers

C. L. Brunet , Rosalind H. Gunby , Roderick S.P. Benson +3 more

Kinetic analysis of dexamethasone-induced apoptosis in the human lymphoblastoid cell line CCRF CEM C7A has revealed a point when cells, morphologically indistinguishable from un...

1998 Cell Death and Differentiation 119 citations

Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1

Maria Chiara Maiuri , Gaëtane Le Toumelin , Alfredo Criollo +10 more

The anti-apoptotic proteins Bcl-2 and Bcl-X(L) bind and inhibit Beclin-1, an essential mediator of autophagy. Here, we demonstrate that this interaction involves a BH3 domain wi...

2007 The EMBO Journal 1070 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 1,189
Institution: University of Manchester

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0002-6661-8175

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.