John Ashburner

The neuroanatomy of autism

Autism is a biological disorder which affects social cognition, and understanding brain abnormalities of the former will elucidate the brain basis of the latter. We report struc...

Spatial registration and normalization of images

Abstract This paper concerns the spatial and intensity transformations that map one image onto another. We present a general technique that facilitates nonlinear spatial (stereo...

Incorporating Prior Knowledge into Image Registration

Voxel-Based Morphometry—The Methods

Nonlinear spatial normalization using basis functions

We describe a comprehensive framework for performing rapid and automatic nonlabel-based nonlinear spatial normalizations. The approach adopted minimizes the residual squared dif...

Multimodal Image Coregistration and Partitioning—A Unified Framework

Correlation between structural and functional changes in brain in an idiopathic headache syndrome

Identifying global anatomical differences: Deformation-based morphometry

The aim of this paper is to illustrate a method for identifying macroscopic anatomical differences among the brains of different populations of subjects. The method involves spa...

Neural basis of an inherited speech and language disorder

Investigation of the three-generation KE family, half of whose members are affected by a pronounced verbal dyspraxia, has led to identification of their core deficit as one invo...

Voxel-by-Voxel Comparison of Automatically Segmented Cerebral Gray Matter—A Rater-Independent Comparison of Structural MRI in Patients with Epilepsy

Kallmann’s syndrome

Although morphometry on its own cannot determine the cause of mirror movements, the specific finding of a hypertrophied corticospinal tract in xKS is consistent with electrophys...

Classical and Bayesian Inference in Neuroimaging: Applications

Classical and Bayesian Inference in Neuroimaging: Theory

A fast diffeomorphic image registration algorithm

This paper describes DARTEL, which is an algorithm for diffeomorphic image registration. It is implemented for both 2D and 3D image registration and has been formulated to inclu...

Unified segmentation

A probabilistic framework is presented that enables image registration, tissue classification, and bias correction to be combined within the same generative model. A derivation ...

A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains

Voxel-based-morphometry (VBM) is a whole-brain, unbiased technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resona...

Computational anatomy with the SPM software

An overview of computational procedures for examining neuroanatomical variability is presented. The review focuses on approaches that can be applied using the SPM software packa...