John Danesh

Analysis of protein-coding genetic variation in 60,706 humans

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

Lipid assessment in vascular disease can be simplified by measurement of either total and HDL cholesterol levels or apolipoproteins without the need to fast and without regard t...

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the presence of an expanded somatic blood-cell clone in persons without other hematologic...

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conducted a multiancestry genome-wide-association meta-analysis in 521,612 individu...