Liisa Holm

A large-scale evaluation of computational protein function prediction

The Pfam protein families database

Pfam is a widely used database of protein families, currently containing more than 13 000 manually curated protein families as of release 26.0. Pfam is available via servers in ...

Touring protein fold space with Dali/FSSP

The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is der...

COFFEE: an objective function for multiple sequence alignments.

Abstract MOTIVATION: In order to increase the accuracy of multiple sequence alignments, we designed a new strategy for optimizing multiple sequence alignments by genetic algorit...