Luke O'neill - Researcher Profile | RDL Research Database

Publications

2 shown

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling

Andrew Bowie , Endre Kiss-Tóth , Julian Symons +3 more

Poxviruses employ many strategies to evade and neutralize the host immune response. In this study, we have identified two vaccinia virus ORFs, termed A46R and A52R, that share a...

2000 Proceedings of the National Academy o... 464 citations

Structural Complementarity of Toll/Interleukin-1 Receptor Domains in Toll-like Receptors and the Adaptors Mal and MyD88

Aisling Dunne , Mikael Ejdebäck , Phumzile L. Ludidi +2 more

The Toll/interleukin 1 receptor (TIR) domain is a region found in the cytoplasmic tails of members of the Toll-like receptor/interleukin-1 receptor superfamily. The domain is es...

2003 Journal of Biological Chemistry 202 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 666
Institution: Roche (United Kingdom)

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0002-4333-2748

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.