Mark D. Robinson

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Abstract Summary: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics a...

A scaling normalization method for differential expression analysis of RNA-seq data

Small-sample estimation of negative binomial dispersion, with applications to SAGE data

We derive a quantile-adjusted conditional maximum likelihood estimator for the dispersion parameter of the negative binomial distribution and compare its performance, in terms o...

Moderated statistical tests for assessing differences in tag abundance

Abstract Motivation: Digital gene expression (DGE) technologies measure gene expression by counting sequence tags. They are sensitive technologies for measuring gene expression ...