Martin Steinegger

Highly accurate protein structure prediction with AlphaFold

Abstract Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. Through an enormous experimental effort ...

ColabFold: making protein folding accessible to all

Abstract ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold’s...

MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets

HH-suite3 for fast remote homology detection and deep protein annotation

Abstract Background HH-suite is a widely used open source software suite for sensitive sequence similarity searches and protein fold recognition. It is based on pairwise alignme...

Clustering huge protein sequence sets in linear time

MMseqs2 desktop and local web server app for fast, interactive sequence searches

Abstract Summary The MMseqs2 desktop and web server app facilitates interactive sequence searches through custom protein sequence and profile databases on personal workstations....