Montgomery Slatkin

Finding the missing heritability of complex diseases

A measure of population subdivision based on microsatellite allele frequencies.

Abstract A new measure of the extent of population subdivision as inferred from allele frequencies at microsatellite loci is proposed and tested with computer simulations. This ...

Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm

We generalize an approach suggested by Hill (Heredity, 33, 229-239, 1974) for testing for significant association among alleles at two loci when only genotype and not haplotype ...

A correction to the exact test based on the Ewens sampling distribution

Summary The exact test for neutrality based on the Ewens sampling distribution described previously (Slatkin, 1994) is not correct. The problem is that the test as described is ...