Publications
5 shownWild-type p53 can inhibit oncogene-mediated focus formation.
Mutant forms of the p53 cellular tumor antigen elicit neoplastic transformation in vitro. Recent evidence indicated that loss of normal p53 expression is a frequent event in cer...
Pathways and therapeutic targets in melanoma
This review aims to summarize the current knowledge of molecular pathways and their clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent years...
Induction of apoptosis in HeLa cells by trans-activation-deficient p53.
The p53 tumor suppressor protein is a transcriptional activator, which can mediate apoptotic cell death in a variety of cell types. To determine whether sequence-specific trans-...
A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis
Human wild-type (wt) p53 can induce apoptosis in transiently transfected H1299 cells maintained at 37 degrees C, whereas tumor-derived mutant forms of p53 (with the mutation Ala...
Frequent Co-Authors
Researcher Info
- h-index
- 5
- Publications
- 5
- Citations
- 3,025
- Institution
- Weizmann Institute of Science
External Links
Identifiers
- ORCID
- 0000-0003-4311-7172
Impact Metrics
h-index: Number of publications with at least h citations each.