Mitochondrial control of nuclear apoptosis.
Anucleate cells can be induced to undergo programmed cell death (PCD), indicating the existence of a cytoplasmic PCD pathway that functions independently from the nucleus. Cytop...
Publications
4 shownBcl-2 inhibits the mitochondrial release of an apoptogenic protease.
Bcl-2 belongs to a family of apoptosis-regulatory proteins which incorporate into the outer mitochondrial as well as nuclear membranes. The mechanism by which the proto-oncogene...
The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
Early in programmed cell death (apoptosis), mitochondrial membrane permeability increases. This is at least in part due to opening of the permeability transition (PT) pore, a mu...
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
In a number of experimental systems, the early stage of the apoptotic process, i.e. the stage which precedes nuclear disintegration, is characterized by the breakdown of the inn...
Frequent Co-Authors
Researcher Info
- h-index
- 4
- Publications
- 4
- Citations
- 3,618
- Institution
- Centre National de la Recherche Scientifique
External Links
Impact Metrics
h-index
4
h-index: Number of publications with at least h citations each.