Tammi L. Vickery

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the...

Genome remodelling in a basal-like breast cancer metastasis and xenograft

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

Purpose To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by developing a risk model that incorporates the gene expression–based...

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.