Todd Wylie

Integrated genomic analyses of ovarian carcinoma

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.

Whole-genome sequencing and variant discovery in C. elegans

Massively parallel sequencing instruments enable rapid and inexpensive DNA sequence data production. Because these instruments are new, their data require characterization with ...

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about 13,000 adults in the United States each year. The treatment of this disease has changed li...