William Stafford Noble

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCO...

Integrative annotation of chromatin elements from ENCODE data

The ENCODE Project has generated a wealth of experimental information mapping diverse chromatin properties in several human cell lines. Although each such data track is independ...

Global mapping of protein-DNA interactions in vivo by digital genomic footprinting

Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays

Transmembrane Topology and Signal Peptide Prediction Using Dynamic Bayesian Networks

Hidden Markov models (HMMs) have been successfully applied to the tasks of transmembrane protein topology prediction and signal peptide prediction. In this paper we expand upon ...