Ann Arbor Center for Independent Living

Estimating the reproducibility of psychological science

Empirically analyzing empirical evidence One of the central goals in any scientific endeavor is to understand causality. Experiments that seek to demonstrate a cause/effect rela...

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Integrated genomic analyses of ovarian carcinoma

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis o...

The National Lung Screening Trial: Overview and Study Design

The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older c...

The use of statistical heuristics in everyday inductive reasoning.

In reasoning about everyday problems, people use statistical heuristics, that is, judgmental tools that are rough intuitive equivalents of statistical principles. Statistical he...

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

Critical dimensions in the choice and maintenance of successful treatments: Strength, integrity, and effectiveness.

Successful clinical practice demands that we use good judgment in choosing optimal treatments for the conditions in question. However, the criteria on which we base our choice a...

Implications of Nonresponse for the Interpretation of Mail Questionnaire Data

Frank discussion of problems and limitations of research procedures and critical tests of their performance are marks of professional maturity. Many procedures can be evaluated ...