Abstract In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive impairment, and dem...
The pathophysiological process of Alzheimer's disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long “preclinical” phase of AD would provide ...
Summary Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usual...
Summary The International League Against Epilepsy ( ILAE ) Classification of the Epilepsies has been updated to reflect our gain in understanding of the epilepsies and their und...
Summary The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures ...
Summary The International League Against Epilepsy ( ILAE ) presents a revised operational classification of seizure types. The purpose of such a revision is to recognize that so...
Abstract During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD) considering the disease as a continuum. Thanks to evolving biomarker resear...
A central challenge in interpreting personal genomes is determining which mutations most likely influence disease. Although progress has been made in scoring the functional impa...
Abstract Objective Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression. Methods Clinical follow‐up was obtained 20 ± 3 months...