Genomics (United Kingdom)

Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Clonal hematopoiesis with somatic mutations is readily detected by means of DNA sequencing, is increasingly common as people age, and is associated with increased risks of hemat...

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined a...

Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)

Abstract Chronic pain is a major source of suffering. It interferes with daily functioning and often is accompanied by distress. Yet, in the International Classification of Dise...

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Genomic atlas of the human plasma proteome

Defining the role of common variation in the genomic and biological architecture of adult human height

JASPAR 2020: update of the open-access database of transcription factor binding profiles

Abstract JASPAR (http://jaspar.genereg.net) is an open-access database of curated, non-redundant transcription factor (TF)-binding profiles stored as position frequency matrices...

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

Abstract The populations of dominant species within the human colonic microbiota can potentially be modified by dietary intake with consequences for health. Here we examined the...