Institute of Neurological Sciences

Chronic inflammation in the etiology of disease across the life span

Mapping of a Gene for Parkinson's Disease to Chromosome 4q21-q23

Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting approximately 1 percent of the population over age 50. Recent ...

Quantifying prion disease penetrance using large population control cohorts

Large genomic reference data sets reveal a spectrum of pathogenicity in the prion protein gene and provide genetic validation for a therapeutic strategy in prion disease.

A large kindred with autosomal dominant Parkinson's disease

Abstract We report two large kindreds with Parkinson's disease (PD) apparently inherited in autosomal dominant fashion. Forty‐one persons in four generations have been affected;...

Snoring every night as a risk factor for myocardial infarction: a case-control study.

Infection with Pasteurella multocida is a common sequel to dog and cat bites.We report on a woman who developed a postoperative infection after encouraging her pet dog to lick h...