Jackson Laboratory

A global reference for human genetic variation

Analysis of protein-coding genetic variation in 60,706 humans

MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights

Abstract Since its first release over a decade ago, the MetaboAnalyst web-based platform has become widely used for comprehensive metabolomics data analysis and interpretation. ...

The Collaborative Cross, a community resource for the genetic analysis of complex traits

The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the format...

Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes

Blood glucose levels are tightly controlled by the coordinated action of at least four cell types constituting pancreatic islets. Changes in the proportion and/or function of th...

The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos

TiO2 pigment technology: a review

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease

The Mouse Genome Database (MGD, http://www.informatics.jax.org) serves the international biomedical research community as the central resource for integrated genomic, genetic an...

Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci

Although genome-wide association studies (GWASs) for nonsyndromic orofacial clefts have identified multiple strongly associated regions, the causal variants are unknown. To addr...