Marine Biological Laboratory

A core gut microbiome in obese and lean twins

Forecasting Agriculturally Driven Global Environmental Change

During the next 50 years, which is likely to be the final period of rapid agricultural expansion, demand for food by a wealthier and 50% larger global population will be a major...

Microbial diversity in the deep sea and the underexplored “rare biosphere”

The evolution of marine microbes over billions of years predicts that the composition of microbial communities should be much greater than the published estimates of a few thous...

Responses of Arctic Tundra to Experimental and Observed Changes in Climate

We manipulated light, temperature, and nutrients in moist tussock tundra near Toolik Lake, Alaska to determine how global changes in these parameters might affect community and ...

Microbial Population Structures in the Deep Marine Biosphere

The analytical power of environmental DNA sequences for modeling microbial ecosystems depends on accurate assessments of population structure, including diversity (richness) and...

The fate of nitrogen and phosphorus at the land-sea margin of the North Atlantic Ocean

Escherichia coli K-12: a cooperatively developed annotation snapshot--2005

The goal of this group project has been to coordinate and bring up-to-date information on all genes of Escherichia coli K-12. Annotation of the genome of an organism entails ide...

Metagenomic study of the oral microbiota by Illumina high-throughput sequencing

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

Cyclin B, a positive regulatory subunit of the cdc2 protein kinase complex, is synthesized across the cell cycle and then rapidly degraded at the end of mitosis. Degradation of ...

The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity

Abstract The neuropathology of Alzheimer's disease (AD) and other tauopathies is characterized by filamentous deposits of the microtubule‐associated protein tau, but the relatio...