Max Planck Institute for Molecular Genetics

A global reference for human genetic variation

The single-cell transcriptional landscape of mammalian organogenesis

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

Transcriptome and genome sequencing uncovers functional variation in humans

<i>Oases:</i>robust<i>de novo</i>RNA-seq assembly across the dynamic range of expression levels

Abstract Motivation: High-throughput sequencing has made the analysis of new model organisms more affordable. Although assembling a new genome can still be costly and difficult,...

Adaptive seeds tame genomic sequence comparison

The main way of analyzing biological sequences is by comparing and aligning them to each other. It remains difficult, however, to compare modern multi-billionbase DNA data sets....

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

The functional complexity of the human transcriptome is not yet fully elucidated. We report a high-throughput sequence of the human transcriptome from a human embryonic kidney a...

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

The ConsensusPathDB interaction database: 2013 update

Knowledge of the various interactions between molecules in the cell is crucial for understanding cellular processes in health and disease. Currently available interaction databa...

The Genetics of Alzheimer Disease: Back to the Future