National Foundation for Cancer Research

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

When the mammalian proto-oncogene bcl-2 is overexpressed it can protect various types of cells both from normal and from experimentally induced apoptosis, but the molecular mech...

Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria

Apoptotic cell death involves a ritual series of morphological changes, presumably reflecting a conserved molecular pathway. We now report that the nuclear events typical of apo...

Assembly and Stability of the Tobacco Mosaic Virus Particle

Neural apoptosis

Abstract Apoptosis is a mode of cell death in which the cell plays an active role in its own demise. The study of neural apoptosis, the identification of genes controlling apopt...

TUMORIGENIC ACTIVITY OF TISSUE CELL CULTURES*