SickKids Foundation

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

Abstract The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the...

Identification of human brain tumour initiating cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

The Diploid Genome Sequence of an Individual Human

Presented here is a genome sequence of an individual human. It was produced from approximately 32 million random DNA fragments, sequenced by Sanger dideoxy technology and assemb...

Defining a Healthy Human Gut Microbiome: Current Concepts, Future Directions, and Clinical Applications

BrainNetCNN: Convolutional neural networks for brain networks; towards predicting neurodevelopment

Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis

These two phase 3 studies show the efficacy of canakinumab in systemic JIA with active systemic features. (Funded by Novartis Pharma; ClinicalTrials.gov numbers, NCT00889863 and...

<scp>I</scp>nternational <scp>S</scp>ociety of <scp>N</scp>europathology‐<scp>H</scp>aarlem <scp>C</scp>onsensus <scp>G</scp>uidelines for <scp>N</scp>ervous <scp>S</scp>ystem <scp>T</scp>umor <scp>C</scp>lassification and <scp>G</scp>rading

Abstract Major discoveries in the biology of nervous system tumors have raised the question of how non‐histological data such as molecular information can be incorporated into t...