The Francis Crick Institute

A framework for advancing our understanding of cancer-associated fibroblasts

Improved protein structure prediction using potentials from deep learning

The nf-core framework for community-curated bioinformatics pipelines

Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic

DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have ent...

Artificial intelligence in cancer imaging: Clinical challenges and applications

Abstract Judgement, as one of the core tenets of medicine, relies upon the integration of multilayered data with nuanced decision making. Cancer offers a unique context for medi...

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

Genetic mechanisms of critical illness in COVID-19

Chromosomal instability drives metastasis through a cytosolic DNA response