The University of Texas MD Anderson Cancer Center

Comprehensive molecular portraits of human breast tumours

Inferring tumour purity and stromal and immune cell admixture from expression data

Infiltrating stromal and immune cells form the major fraction of normal cells in tumour tissue and not only perturb the tumour signal in molecular studies but also have an impor...

The biology <b>,</b> function <b>,</b> and biomedical applications of exosomes

Clinical uses of cellular communication Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them. They are t...

The Cancer Genome Atlas Pan-Cancer analysis project

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Integrated genomic analyses of ovarian carcinoma

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

Antibody-mediated blockade of PD-L1 induced durable tumor regression (objective response rate of 6 to 17%) and prolonged stabilization of disease (rates of 12 to 41% at 24 weeks...

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

In patients with unresectable hepatocellular carcinoma, atezolizumab combined with bevacizumab resulted in better overall and progression-free survival outcomes than sorafenib. ...

The Immune Landscape of Cancer

We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identi...