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Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Knee Arthroplasty

Rivaroxaban was superior to enoxaparin for thromboprophylaxis after total knee arthroplasty, with similar rates of bleeding. (ClinicalTrials.gov number, NCT00361894.)

Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

Although the incidence of hepatocellular carcinoma (HCC) is increasing in the United States, data from large prospective studies are limited. We evaluated the Hepatitis C Antivi...

Des-γ-Carboxy Prothrombin and α-Fetoprotein as Biomarkers for the Early Detection of Hepatocellular Carcinoma

The outcome of patients with hepatocellular carcinoma (HCC) remains poor because of late diagnosis. The aim of this study was to compare the accuracy of alpha-fetoprotein (AFP) ...

Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes

SUMMARY There is ample evidence that cells of higher eukaryotes express double-stranded RNA molecules (dsRNAs) either naturally or as the result of viral infection or aberrant, ...

Effect of Noncompetitive Blockade of <i>N</i>‐Methyl‐d‐Aspartate Receptors on the Neurochemical Sequelae of Experimental Brain Injury

Abstract: Pharmacological inhibition of excitatory neurotransmission attenuates cell death in models of global and focal ischemia and hypoglycemia, and improves neurological out...

Blood Pressure Trajectories in the 20 Years Before Death

Mean SBP and DBP decreased for more than a decade before death in patients dying at 60 years and older. These BP decreases are not simply attributable to age, treatment of hyper...

Transmural gradients of left ventricular tissue metabolites after circumflex artery ligation in dogs