VIB-KU Leuven Center for Cancer Biology - Academic Profile

Publications

Mutational Processes Molding the Genomes of 21 Breast Cancers

Serena Nik‐Zainal , Ludmil B. Alexandrov , David C. Wedge +50 more

2012 Cell 1933 citations

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang , Li Ding , Linda Holmfeldt +66 more

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...

2012 Nature 1596 citations

The Life History of 21 Breast Cancers

Serena Nik‐Zainal , Peter Van Loo , David C. Wedge +46 more

2012 Cell 1475 citations

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

Joke Comijn , Geert Berx , Petra Vermassen +6 more

2001 Molecular Cell 1370 citations

Allele-specific copy number analysis of tumors

Peter Van Loo , Silje Nord , Ole Christian Lingjærde +10 more

We present an allele-specific copy number analysis of the in vivo breast cancer genome. We describe a unique bioinformatics approach, ASCAT (allele-specific copy number analysis...

2010 Proceedings of the National Academy o... 1266 citations

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

Kim De Keersmaecker , Zeynep Kalender Atak , Ning Li +27 more

2012 Nature Genetics 416 citations

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

Corinna Köhler , David Nittner , Florian Rambow +10 more

2017 Cell stem cell 129 citations

Affiliated Researchers

Institution Info

Type: facility
Country: BE
Publications: 7
Citations: 8,185

External Links

Identifiers

ROR: https://ror.org/00eyng893