Vlaams Instituut voor Biotechnologie

Angiogenesis in cancer and other diseases

Pathological angiogenesis is a hallmark of cancer and various ischaemic and inflammatory diseases. Concentrated efforts in this area of research are leading to the discovery of ...

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

The endothelial cell-specific vascular endothelial growth factor (VEGF) and its cellular receptors Flt-1 and Flk-1 have been implicated in the formation of the embryonic vascula...

Mechanisms of angiogenesis and arteriogenesis

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Nonrandom divergence of gene expression following gene and genome duplications in the flowering plant Arabidopsis thaliana

Abstract Background Genome analyses have revealed that gene duplication in plants is rampant. Furthermore, many of the duplicated genes seem to have been created through ancient...

The Automatic Detection of Homologous Regions (ADHoRe) and Its Application to Microcolinearity Between <i>Arabidopsis</i> and Rice

It is expected that one of the merits of comparative genomics lies in the transfer of structural and functional information from one genome to another. This is based on the obse...

Controlling the cellular brakes