Walter and Eliza Hall Institute of Medical Research

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Abstract Summary: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics a...

limma powers differential expression analyses for RNA-sequencing and microarray studies

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. limma is an R/Bioconductor software package that provides an integrated solution ...

Bioconductor: open software development for computational biology and bioinformatics

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

The problem of identifying differentially expressed genes in designed microarray experiments is considered. Lonnstedt and Speed (2002) derived an expression for the posterior od...

A comparison of normalization methods for high densityoligonucleotide array data based on variance and bias

Abstract Motivation: When running experiments that involve multiple high density oligonucleotide arrays, it is important to remove sources of variation between arrays of non-bio...

A scaling normalization method for differential expression analysis of RNA-seq data

Integrated genomic analyses of ovarian carcinoma

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemic...

Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells

A workshop was convened by the AACR to discuss the rapidly emerging cancer stem cell model for tumor development and progression. The meeting participants were charged with eval...