Wellcome Centre for Human Neuroimaging

A fast diffeomorphic image registration algorithm

This paper describes DARTEL, which is an algorithm for diffeomorphic image registration. It is implemented for both 2D and 3D image registration and has been formulated to inclu...

Nonlinear spatial normalization using basis functions

We describe a comprehensive framework for performing rapid and automatic nonlabel-based nonlinear spatial normalizations. The approach adopted minimizes the residual squared dif...

Brain Systems Mediating Aversive Conditioning: an Event-Related fMRI Study

The rises and falls of disconnection syndromes

In a brain composed of localized but connected specialized areas, disconnection leads to dysfunction. This simple formulation underlay a range of 19th century neurological disor...

Computational anatomy with the SPM software

An overview of computational procedures for examining neuroanatomical variability is presented. The review focuses on approaches that can be applied using the SPM software packa...

The neuroanatomy of autism

Autism is a biological disorder which affects social cognition, and understanding brain abnormalities of the former will elucidate the brain basis of the latter. We report struc...

Identifying global anatomical differences: Deformation-based morphometry

The aim of this paper is to illustrate a method for identifying macroscopic anatomical differences among the brains of different populations of subjects. The method involves spa...

Mixed-effects and fMRI studies