[ 11 C]PIB in a nondemented population

Mark A. Mintun; Gina LaRossa; Yvette I. Sheline; Carmen S. Dence; S. Y. Lee; Robert H. Mach; William E. Klunk; Chester A. Mathis; Steven T. DeKosky; John C. Morris

doi:10.1212/01.wnl.0000228230.26044.a4

Abstract

Elevated [(11)C]PIB binding in nondemented subjects suggests that [(11)C]PIB amyloid imaging may be sensitive for detection of a preclinical Alzheimer disease state. Longitudinal studies will be required to determine the association of elevated [(11)C]PIB binding and risk of developing dementia of the Alzheimer type.

Keywords

Pittsburgh compound BPrecuneusAlzheimer's diseasePsychologyPathologyPopulationDementiaCentral nervous system diseaseMedicineNeuroscienceDiseaseCognition

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Publication Info

Year: 2006
Type: article
Volume: 67
Issue: 3
Pages: 446-452
Citations: 1029
Access: Closed

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APA Style

                            
                                
                                    Mark A. Mintun, 
                                
                                    Gina LaRossa, 
                                
                                    Yvette I. Sheline
                                
                                et al.
                            
                            (2006). 
                            [ <sup>11</sup> C]PIB in a nondemented population. 
                            Neurology
                            , 67
                            (3)
                            , 446-452.
                            https://doi.org/10.1212/01.wnl.0000228230.26044.a4
                        

Identifiers

DOI: 10.1212/01.wnl.0000228230.26044.a4

[ <sup>11</sup> C]PIB in a nondemented population