10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

Abstract

Despite an early loss of glycemic differences, a continued reduction in microvascular risk and emergent risk reductions for myocardial infarction and death from any cause were observed during 10 years of post-trial follow-up. A continued benefit after metformin therapy was evident among overweight patients. (UKPDS 80; Current Controlled Trials number, ISRCTN75451837.)

Keywords

MedicineUnited Kingdom Prospective Diabetes StudyGlycated hemoglobinMetforminType 2 diabetesInternal medicineDiabetes mellitusMyocardial infarctionSulfonylureaClinical endpointType 2 Diabetes MellitusInsulinRandomized controlled trialEndocrinology

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Publication Info

Year: 2008
Type: article
Volume: 359
Issue: 15
Pages: 1577-1589
Citations: 7594
Access: Closed

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APA Style

                            
                                
                                    Rury R. Holman, 
                                
                                    Sanjoy K. Paul, 
                                
                                    M. Angelyn Bethel
                                
                                et al.
                            
                            (2008). 
                            10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes. 
                            New England Journal of Medicine
                            , 359
                            (15)
                            , 1577-1589.
                            https://doi.org/10.1056/nejmoa0806470
                        

Identifiers

DOI: 10.1056/nejmoa0806470