Abstract
Abstract Summary: We describe the creation of a test set containing secretory and non-secretory proteins. Five existing prediction programs for signal sequences and their cleavage sites are compared on the basis of this test set: SPScan, SigCleave, SignalP V1.1, SignalP V2.0.b2-HMM and SignalP V2.0.b2-NN. Availability: Detailed results, the test set and the script to create the test set are available at ftp://ftp.ebi.ac.uk/pub/contrib/swissprot/testsets/signal/ Contact: hhe@ebi.ac.uk
Keywords
Signal peptideSIGNAL (programming language)Set (abstract data type)Sequence (biology)Test setSecretory proteinComputer scienceSecretory pathwayCleavage (geology)Protein sequencingComputational biologyPeptide sequencePattern recognition (psychology)Artificial intelligenceBiologyBiochemistrySecretionGeneGolgi apparatus
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Publication Info
- Year
- 2000
- Type
- article
- Volume
- 16
- Issue
- 8
- Pages
- 741-742
- Citations
- 127
- Access
- Closed
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Cite This
Kerstin M. L. Menne,
Henning Hermjakob,
Rolf Apweiler
(2000).
A comparison of signal sequence prediction methods using a test set of signal peptides.
Bioinformatics
, 16
(8)
, 741-742.
https://doi.org/10.1093/bioinformatics/16.8.741
Identifiers
- DOI
- 10.1093/bioinformatics/16.8.741