Abstract Optically active oxirane‐2‐carboxylic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide. The azido alcohols obtained were subsequently converted into aziridine‐2‐carboxylic esters by reaction with triphenylphosphine, in good yields and with high optical purity. Various racemic oxirane‐2‐carboxylic esters were subjected to the same sequence of reactions.
Abstract Treatment of 3‐bromo3‐methyl‐1‐butyne ( 1 ) or 1‐iodo‐3‐methyl‐1,2‐butadiene ( 3 ) with solutions of sodium azide affords 3‐azido‐3‐methyl‐1‐butyne ( 5 ) which reacts a...
The cycloaddition of azides to alkynes is one of the most important synthetic routes to 1H-[1,2,3]-triazoles. Here a novel regiospecific copper(I)-catalyzed 1,3-dipolar cycloadd...
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to...
ABSTRACT 3-Methyl-1-phenyl-2-phospholene and 1-phenyl-2-phospholene 1-oxides were converted into 2-bromo-3-hydroxy-3-methyl-1-phenylphospholane and 2-bromo-3-hydroxy-1-phenylpho...
Abstract Upon reaction of zirconium alkoxides, Zr(OR) 4 , with carboxylic acids, the clusters Zr 6 O 4 (OH) 4 (OOCR) 12 ( Zr6 ) or [Zr 6 O 4 (OH) 4 (OOCR) 12 ] 2 ( Zr12 ) were o...
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