Keywords
Affiliated Institutions
Related Publications
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
Macrophages orchestrate innate immunity by phagocytosing pathogens and coordinating inflammatory responses. Effective defence requires the host to discriminate between different...
Phylogenetic Perspectives in Innate Immunity
The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlig...
The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6)
The human homologue of Drosophila Toll (hToll) is a recently cloned receptor of the interleukin 1 receptor (IL-1R) superfamily, and has been implicated in the activation of adap...
Toll-Like Receptors
The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defen...
Toll-Like Receptor Signaling and Regulation of Cytokine Gene Expression in the Immune System
Dendritic cells, macrophages, and granulocytes are derived from hematopoietic stem cells and provide a first line of defense against infectious pathogens. Toll-like receptors (T...
Publication Info
- Year
- 1997
- Type
- article
- Volume
- 388
- Issue
- 6640
- Pages
- 394-397
- Citations
- 5502
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1038/41131