A Modified Poisson Regression Approach to Prospective Studies with Binary Data

2004 American Journal of Epidemiology 8,906 citations

Abstract

Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.

Keywords

Poisson regressionStatisticsPoisson distributionMathematicsRegression analysisBinary dataRegressionVariance (accounting)Linear regressionBinary numberEconometricsMedicinePopulation

MeSH Terms

Clinical Trials as TopicData InterpretationStatisticalHumansPoisson DistributionProspective StudiesRegression AnalysisReproducibility of ResultsRisk

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Publication Info

Year
2004
Type
article
Volume
159
Issue
7
Pages
702-706
Citations
8906
Access
Closed

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8906
OpenAlex
90
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7859
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Cite This

Guangyong Zou (2004). A Modified Poisson Regression Approach to Prospective Studies with Binary Data. American Journal of Epidemiology , 159 (7) , 702-706. https://doi.org/10.1093/aje/kwh090

Identifiers

DOI
10.1093/aje/kwh090
PMID
15033648

Data Quality

Data completeness: 86%