A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

Zizhen Yao; Cindy T. J. van Velthoven; Thuc Nghi Nguyen; Jeff Goldy; Adriana E. Sedeño-Cortés; Fahimeh Baftizadeh; Darren Bertagnolli; Tamara Casper; Megan Chiang; Kirsten Crichton; Song‐Lin Ding; Olivia Fong; Emma Garren; Alexandra Glandon; Nathan W. Gouwens; J. Gray; Lucas T. Graybuck; Michael Hawrylycz; Daniel Hirschstein; Matthew Kroll; Kanan Lathia; Changkyu Lee; Boaz P. Levi; Delissa McMillen; Stephanie Mok; Thanh Pham; Qingzhong Ren; Christine Rimorin; Nadiya V. Shapovalova; Josef Šulc; Susan M. Sunkin; Michael Tieu; Amy Torkelson; Herman Tung; Katelyn Ward; Nick Dee; Kimberly A. Smith; Bosiljka Tasic; Hongkui Zeng

doi:10.1016/j.cell.2021.04.021

Keywords

SubiculumBiologyHippocampal formationNeuroscienceGlutamatergicCell typeGABAergicSet (abstract data type)CellComputer scienceGeneticsGlutamate receptorReceptor

Affiliated Institutions

Related Publications

Shared and distinct transcriptomic cell types across neocortical areas

Bosiljka Tasic , Zizhen Yao , Lucas T. Graybuck +45 more

The neocortex contains a multitude of cell types that are segregated into layers and functionally distinct areas. To investigate the diversity of cell types across the mouse neo...

2018 Nature 1858 citations

GABAergic Excitation Promotes Neuronal Differentiation in Adult Hippocampal Progenitor Cells

Yusuke Tozuka , Satoshi Fukuda , Takashi Namba +2 more

Hippocampal activity influences neurogenesis in the adult dentate gyrus; however, little is known about the involvement of the hippocampal circuitry in this process. In the subg...

2005 Neuron 723 citations

Molecular Architecture of the Mouse Nervous System

Amit Zeisel , Hannah Hochgerner , Peter Lönnerberg +17 more

The mammalian nervous system executes complex behaviors controlled by specialized, precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a milli...

2018 Cell 2729 citations

Depolarizing GABA Acts on Intrinsically Bursting Pyramidal Neurons to Drive Giant Depolarizing Potentials in the Immature Hippocampus

Sampsa T. Sipilä , Kristiina Huttu , Iván Soltész +2 more

Spontaneous periodic network events are a characteristic feature of developing neuronal networks, and they are thought to play a crucial role in the maturation of neuronal circu...

2005 Journal of Neuroscience 182 citations

Single-cell transcriptomic analysis of Alzheimer’s disease

Hansruedi Mathys , José Dávila-Velderrain , Zhuyu Peng +13 more

Alzheimer's disease is a pervasive neurodegenerative disorder, the molecular complexity of which remains poorly understood. Here, we analysed 80,660 single-nucleus transcriptome...

2019 Nature 2450 citations

Publication Info

Year: 2021
Type: article
Volume: 184
Issue: 12
Pages: 3222-3241.e26
Citations: 1021
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1021

OpenAlex

Cite This

APA Style

                            
                                
                                    Zizhen Yao, 
                                
                                    Cindy T. J. van Velthoven, 
                                
                                    Thuc Nghi Nguyen
                                
                                et al.
                            
                            (2021). 
                            A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation. 
                            Cell
                            , 184
                            (12)
                            , 3222-3241.e26.
                            https://doi.org/10.1016/j.cell.2021.04.021
                        

Identifiers

DOI: 10.1016/j.cell.2021.04.021