Active domains in wild-type and mutant glucocorticoid receptors.

Hans-Georg Dellweg; Agnes Hotz; Katrin Mugele; Ulrich Gehring

doi:10.1002/j.1460-2075.1982.tb01161.x

Keywords

Glucocorticoid receptorReceptorMutantWild typeBiologyGlucocorticoidMolecular biologyStereochemistryBiochemistryChemistryEndocrinologyGene

Affiliated Institutions

Heidelberg University DE

Related Publications

Molecular Dynamics Simulations of Ligand Dissociation from Thyroid Hormone Receptors: Evidence of the Likeliest Escape Pathway and Its Implications for the Design of Novel Ligands

Leandro Martı́nez , Paul Webb , Igor Polikarpov +1 more

Steered molecular dynamics simulations of ligand dissociation from Thyroid hormone receptors indicate that dissociation is favored via rearrangements in a mobile part of the LBD...

2005 Journal of Medicinal Chemistry 83 citations

Environmentally persistent alkylphenolic compounds are estrogenic.

R White , Susan Jobling , Susan Hoare +2 more

We show that a number of alkylphenolic compounds, used in a variety of commercial products and found in river water, are estrogenic in fish, birds, and mammals. 4-Octylphenol (O...

1994 Endocrinology 1384 citations

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation.

Michael A. Kjelsberg , Susanna Cotecchia , Jerzy Ostrowski +2 more

Mutations in an intracellular region of the alpha 1B-adrenergic receptor constitutively activate the receptor, resulting in G protein coupling in the absence of agonist, as evid...

1992 Journal of Biological Chemistry 599 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

Stanley M. Hollenberg , Cary Weinberger , Estelita S. Ong +6 more

1985 Nature 1859 citations

Glucocorticoid Action on Hybrid Clones Derived from Cultured Myeloma and Lymphoma Cell Lines

Ulrich Gehring , Behzad Mohit , Gordon M. Tomkins

Cells of a cloned myeloma line from a Balb/c mouse contain specific cytoplasmic glucocorticoid receptors and are killed by dexamethasone. Cells of a lymphoma line (from mouse st...

1972 Proceedings of the National Academy o... 43 citations

Publication Info

Year: 1982
Type: article
Volume: 1
Issue: 3
Pages: 285-289
Citations: 80
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Active domains in wild-type and mutant glucocorticoid receptors.

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                
                                    Hans-Georg Dellweg, 
                                
                                    Agnes Hotz, 
                                
                                    Katrin Mugele
                                
                                et al.
                            
                            (1982). 
                            Active domains in wild-type and mutant glucocorticoid receptors.. 
                            The EMBO Journal
                            , 1
                            (3)
                            , 285-289.
                            https://doi.org/10.1002/j.1460-2075.1982.tb01161.x
                        

Identifiers

DOI: 10.1002/j.1460-2075.1982.tb01161.x