Abstract

Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.

Keywords

MedicineMyocardial infarctionCardiologyInternal medicineCoronary atherosclerosisCoronary angiographyRisk stratificationAcute coronary syndromePathogenesisCoronary artery disease

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Publication Info

Year
2014
Type
review
Volume
36
Issue
8
Pages
475-481
Citations
356
Access
Closed

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Giampaolo Niccoli, Giancarla Scalone, Filippo Crea (2014). Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management. European Heart Journal , 36 (8) , 475-481. https://doi.org/10.1093/eurheartj/ehu469

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DOI
10.1093/eurheartj/ehu469