Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer

Yasutaka Sukawa; Hiroyuki Yamamoto; Katsuhiko Nosho; Hiroaki Kunimoto; Hiromu Suzuki; Yasushi Adachi; Mayumi Nakazawa; Takayuki Nobuoka; Mariko Kawayama; Masashi Mikami; Takashi Matsuno; Tadashi Hasegawa; Koichi Hirata; Kohzoh Imai; Yasuhisa Shinomura

doi:10.3748/wjg.v18.i45.6577

Abstract

HER2 expression, PIK3CA mutations and EBV infection in gastric cancer were characterized. pAkt expression significantly correlates with HER2 expression and with a poor prognosis.

Keywords

ImmunohistochemistryCancerCancer researchBiologyThymomaMicrosatellite instabilityEpidermal growth factor receptorOncogenePathologyPI3K/AKT/mTOR pathwayMedicineInternal medicineSignal transductionGeneCell cycle

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Publication Info

Year: 2012
Type: article
Volume: 18
Issue: 45
Pages: 6577-6577
Citations: 84
Access: Closed

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APA Style

                            
                                
                                    Yasutaka Sukawa, 
                                
                                    Hiroyuki Yamamoto, 
                                
                                    Katsuhiko Nosho
                                
                                et al.
                            
                            (2012). 
                            Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer. 
                            World Journal of Gastroenterology
                            , 18
                            (45)
                            , 6577-6577.
                            https://doi.org/10.3748/wjg.v18.i45.6577
                        

Identifiers

DOI: 10.3748/wjg.v18.i45.6577