Abstract
Antibiotic use is common in childhood and its potential as an environmental risk factor for IBD warrants scrutiny. This is the first prospective study to show a strong association between antibiotic use and CD in childhood. However, as with any observational study, causality cannot be inferred from our results and confounding by indication--in particular, prescribing of antibiotics to children with intestinal symptoms of as yet undiagnosed CD--should also be considered as a possible explanation.
Keywords
MedicineAntibioticsInflammatory bowel diseaseConfoundingMedical prescriptionRelative riskInternal medicineProspective cohort studyCohort studyPoisson regressionPediatricsObservational studyRate ratioDiseaseEnvironmental healthPopulationConfidence intervalBiologyMicrobiology
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Publication Info
- Year
- 2010
- Type
- article
- Volume
- 60
- Issue
- 1
- Pages
- 49-54
- Citations
- 483
- Access
- Closed
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Cite This
Anders Hviid,
Henrik Svanström,
Morten Frisch
(2010).
Antibiotic use and inflammatory bowel diseases in childhood.
Gut
, 60
(1)
, 49-54.
https://doi.org/10.1136/gut.2010.219683
Identifiers
- DOI
- 10.1136/gut.2010.219683