Antithrombotic Therapy To Prevent Stroke in Patients with Atrial Fibrillation

Abstract

Adjusted-dose warfarin and aspirin reduce stroke in patients with atrial fibrillation, and warfarin is substantially more efficacious than aspirin. The benefit of antithrombotic therapy was not offset by the occurrence of major hemorrhage among participants in randomized trials. Judicious use of antithrombotic therapy, tailored according to the inherent risk for stroke, importantly reduces stroke in patients with atrial fibrillation.

Keywords

MedicineAntithromboticAspirinWarfarinAtrial fibrillationStroke (engine)Randomized controlled trialXimelagatranInternal medicineFibrinolytic agentAbsolute risk reductionCardiologyConfidence intervalDabigatran

Affiliated Institutions

The University of Texas Health Science Center at San Antonio US

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Publication Info

Year: 1999
Type: review
Volume: 131
Issue: 7
Pages: 492-501
Citations: 1627
Access: Closed

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APA Style

                            
                                
                                    Robert G. Hart, 
                                
                                    Oscar Benavente, 
                                
                                    Ruth McBride
                                
                                et al.
                            
                            (1999). 
                            Antithrombotic Therapy To Prevent Stroke in Patients with Atrial Fibrillation. 
                            Annals of Internal Medicine
                            , 131
                            (7)
                            , 492-501.
                            https://doi.org/10.7326/0003-4819-131-7-199910050-00003
                        

Identifiers

DOI: 10.7326/0003-4819-131-7-199910050-00003