APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

Yuan-Ta Lin; Jinsoo Seo; Fan Gao; Heather Feldman; Hsin-Lan Wen; Jay Penney; Hugh P. Cam; Elizabeta Gjoneska; Waseem Raja; Jemmie Cheng; Richard Rueda; Oleg Kritskiy; Fatema Abdurrob; Zhuyu Peng; Blerta Milo; Chung Jong Yu; Sara Elmsaouri; Dilip Dey; Tak Ko; Bruce A. Yankner; Li‐Huei Tsai

doi:10.1016/j.neuron.2018.05.008

Keywords

PhenotypeNeuroscienceDiseaseHuman brainCellAlzheimer's diseaseBiologyCell typeMammalian brainMedicineGeneticsGenePathology

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Publication Info

Year: 2018
Type: article
Volume: 98
Issue: 6
Pages: 1141-1154.e7
Citations: 1082
Access: Closed

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APA Style

                            
                                
                                    Yuan-Ta Lin, 
                                
                                    Jinsoo Seo, 
                                
                                    Fan Gao
                                
                                et al.
                            
                            (2018). 
                            APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types. 
                            Neuron
                            , 98
                            (6)
                            , 1141-1154.e7.
                            https://doi.org/10.1016/j.neuron.2018.05.008
                        

Identifiers

DOI: 10.1016/j.neuron.2018.05.008