Approaches to Synthesis of DCL-Based PSMA Ligands

Nikolay Y. Zyk; Nina S. Boutakova; Aleksei E. Machulkin; Елена К. Белоглазкина

doi:10.20944/preprints202512.0751.v1

Abstract

Currently, prostate specific membrane antigen ligands are one of the most widely used platforms for creating compounds targeting prostate cancer tumor cells. In this mini-review, we have collected and systematized existing approaches to the synthesis of PSMA ligands based on DCL urea, as the most widely used vector platform. The main approaches to each stage of the synthesis of PSMA inhibitors of various structures are considered in detail, and existing synthetic techniques are collected and analyzed.

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Year: 2025
Type: article
Citations: 0
Access: Closed

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APA Style

                            
                                    Nikolay Y. Zyk, 
                                
                                    Nina S. Boutakova, 
                                
                                    Aleksei E. Machulkin
                                
                                et al.
                            
                            (2025). 
                            Approaches to Synthesis of DCL-Based PSMA Ligands. 
                            Preprints.org
                            
                            .
                            https://doi.org/10.20944/preprints202512.0751.v1

Identifiers

DOI: 10.20944/preprints202512.0751.v1